Postdoctoral Researcher – Cellular and Molecular Immunology

Recently formed Cellular and Molecular Immunology Group headed by Dr. Jan Fric in Center for Translational Medicine of The International Clinical Research Center (ICRC) of St. Anne's University Hospital in Brno, Czech Republic is now seeking for a highly motivated and skilled Postdoctoral Researcher to join our international team.

Research focus:

The Cellular and Molecular Immunoregulation group is determined to dissect cell signaling, which controls innate immune response. CMI develops experimental models addressing the role of hematopoietic precursors and mesenchymal stem cells in orchestrating immune response and tissue regeneration. Furthermore, CMI studies unresolved aspects of pattern recognition receptors (including Toll-like receptors) signaling pathways in peripheral blood monocytes in context of inflammation and immunosenescence. These signaling pathways are main sensors of infection and tissue damage and play crucial role in control of acute and chronic inflammatory disorders accompanying for example tissue regeneration or ageing processes. Better understanding of pattern recognition receptors signaling may lead to new strategies for therapeutic control of inflammatory disorders. Mucosal Immunol., 2016, doi:10.1038/mi.2016.52, Front. Immunol. 4, 513 (2014), Stem Cells 32, 3232-3244 (2014), Blood 120, 1380-1389 (2012), EMBO Mol Med 4, 269-282 (2012).


The International Clinical Research Center of St. Anne's University Hospital in Brno (FNUSA-ICRC), Czech Republic is a new-generation research center focusing on the pathogenesis of diseases including finding new methods, technologies and medicaments for effective prevention, early diagnostics and individualized treatment.

We are a top Central European research center with more than 200 researchers, new technologies and experience in using EU grant support. Our partners are world-class research centers and universities.

More abuot FNUSA-ICRC at:

Starting Date: Immediate (negotiable)

FTE: 1 FTE (full-time assignment)

Job Description – you will:

  • Undertake independent research under the direction of the Principal Investigator
  • Design, perform and analyze experiments and write papers
  • Acquire new technical skills as required by the project
  • Write, edit and submit manuscripts/abstracts detailing the results of the project
  • Supervise students and younger colleagues and assist with writing grant applications
  • Present at conferences and workshops
  • Work with cell cultures and peripheral blood cells from donors and patients; analyze inflammatory signalling processes by cellular and molecular immunology techniques.

Desirable Qualifications:

  • Experience in cellular and molecular immunology including cell culture, signaling, transcriptional regulation and gene expression analysis, cloning and protein assays
  • Experience with flow cytometry and confocal microscopy
  • An interest in biology of myeloid cells functions and cell signaling, chronic inflammation, immunosenescence or hematopoiesis and ev. research experience in the derivation and characterization of differentiated cell types from human stem cells and/or experience with complex cellular systems (e.g. co-culture, 3D cell culture) would be an advantage
  • Fluency in English
  • Well organized, responsible, self-motivated, creative and flexible attitude
  • Positive and team-work personality

We offer:

  • Working in international multidisciplinary team with experts in stem cells field, cell signaling, cell imaging
  • Engagement in ambitious projects of basic and clinical immunology
  • Work in an inspiring and highly collaborative environment using state-of-the-art technologies
  • Opportunities for further education and training
  • Competitive salary, 5-wwek of holidays, fix-term contract

How to apply:

The candidates are invited to send their curriculum vitae, cover letter describing motivation and previous experience and contact for 2 references to

We are looking forward to hearing from you!


We are pleased to consider all qualified applicants for employment without regard to age, gender, marital status, sexual orientation, race, color, religion, ethnicity, disability, national origin, nationality, political opinion or any other aspect unrelated to work.

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