Giancarlo Forte lectured at the University of Trieste
27. 8. 2019
Giancarlo Forte, Head of the Cardiovascular System - Mechanobiology Team of FNUSA-ICRC was invited as one of the speakers at the University of Trieste, where he lectured to the students of the Summer School entitled “Nonlinear Life”.
This is the third year of this event, which was founded by the Technical University of Riga. This year's co-organizer is the University of Trieste. "Nonlinear Life is an event for twenty-five master, postgraduate or doctoral students from around the world," explained Giancarlo Forte, adding: "My lecture´s topic was Mechanically activated intracellular pathways in cell function and disease."
Students will learn about the latest trends in the fields of biomedical engineering, medical technologies or life sciences through lectures by professors from Italy, Latvia and other countries within ten days. In addition to the theoretical part, participants can learn about state-of-the-art instruments and procedures in research institutions such as Elettra Sincotrone Trieste.
The supervisory audit mandated compliance with standards and process management
23. 8. 2019 |
On July 22, 2019, external supervisory audit of quality systems according to ČSN EN ISO 9001:2016 took place in the Clinical-Pharmacological Unit (CPU) of the The International Clinical Research Center of St. Anne's University Hospital Brno and Blood bank. During the surveillance audit, no errors were found that would require withdrawal of the certificates, and in the final evaluation it was recommended to retain all the certificates for the above-mentioned quality systems. This certificate confirms compliance with standards related to process management, documentation and business organization.
"The quality system is an essential part of the operation of the CPU to ensure the highest standards when testing new drugs on patients or volunteers," added MVDr. Ing. Václav Trojan Ph.D., Head of Clinical-Pharmacological Unit. "This is another step for our unit to be able to validate the basic research findings not only of the medical cannabis we are preparing, but also of other medicines."
First EHRA accreditation in the Czech Republic awarded to the ICE team
22. 8. 2019 |
The research team of FNUSA-ICRC Interventional Cardiac Electrophysiology (ICE) was the first in the Czech Republic to be accredited as a recognized training centers by the European Heart Rhythm Association (EHRA). "This is a major achievement," said Guido Caluori, research coordinator of the ICE team, "and it is the first step towards building an EP training center in Brno with internationally recognized standards for both Czech and foreign candidates. It also serves to further put FNUSA-ICRC on the main stage of international cardiovascular research."
EHRA (European Hearth Rhythm Association) is a branch of the European Society of Cardiology (ESC). The mission of the association is improving the quality of life and reducing sudden cardiac death by limiting the impact of heart rhythm disturbances. EHRA has more than 3 500 members from across the world including physicians, arrhythmologists, young electrophysiologists, nurses and other professionals.
World experts in enzyme kinetics met in Brno
21. 8. 2019 |
Enzyme kinetics is one of the scientific disciplines, which can not do without the top equipment not only in the field of instruments, but also dynamic software. The world leader in the development of these sophisticated devices and programs is KinTek Corp. Founded by Kenneth A. Johnson.
And on his initiative and with his participation, New Enzymology Kinetics Workshops are held. The thirteenth edition took place at the beginning of the summer for the first time in Europe - in Brno. The main local organizer was prof. RNDr. Zbyněk Prokop Ph.D., member of the FNUSA-ICRC Protein Engineering research team. Thirty-two participants from all over the world gathered at the event, including academic (University of Cambridge, University of Boston, University of Münster, Francis Crick Institute) and commercial area (Roche, MyoKardia, Pentapharm, Tango Therapoeutics, etc.).
Over the four days, participants learned modern kinetic methods associated with high-resolution structural data, which provide a powerful tool for determining reaction mechanisms. Modern kinetic analysis has been described in detail using various kinetic and equilibrium methods using numerous examples of proteins and nucleic acids. The course also focused on developing the path from experimental design to data collection and analysis to gain new mechanistic perspectives. "The workshop was successful not only in terms of scientific content, it also provided a unique space for creating new international contacts," added Professor Prokop in the evaluation of the event.
Professor Hort was appointed Courtesy Professor at the University of South Florida
20. 8. 2019 |
Head of the FNUSA-ICRC Research Dementia (DMT) MUDr. Jakub Hort was appointed Courtesy Professor at the University of South Florida.
This prestigious award further strengthens thelong term ties between the DMT research team and the American University The relationship includes almost a decade of student exchanges, dozens of publications, and other important scientific and academic outcomes. Dr. Hort has played a pivotal role in establishing and nurturing the relationship between his research group and researchers at USF.
"Collaboration with colleagues at the University of South Florida is long-term, constantly evolving, and younger colleagues are also involved in the research, which is reflected in an increase in publications and scientific stays on both sides," Hort added.
Can we improve cardiovascular risk awareness in the Czech Republic?
12. 8. 2019 |
Dr. Jose Pantaleon Hernandez-Rodriguez is a Spanish scientist who has been working for almost a year at the International Clinical Research Center of St. Anne's University Hospital in Brno. His has an interest in cardiovascular diseases, and he would like to develop and implement health initiatives in this city, through his expertise in prevention programs. We have asked him how he can compare his pubic health experience in Western countries, with that of the Czech republic.
José, could you briefly describe your career so far?
I have worked for the National Health Service, in the UK, both as a Public Health information Officer and as well as in commissioning roles. Following my training, in Oxford School of Medical Sciences, I have worked as a project manager and in consultancy roles, in England. I am now based in Brno, and I would like to improve the health of communities through public health prevention programmes.
And what are you doing now?
My interests includes studying the awareness of cardiovascular risks, here in Brno. This is a interesting topic, while Western state-supported campaigns to improve prevention and healthy lifestyle have had measurable impacts, that of Central and Eastern Europe is not well-know. I often see here agressive advertising of alcoholic beverages and tobacco. I would like to improve this.
Is it real at all?
There are very real differences between cardiovascular mortality in western and eastern Europe. The Czech Republic has a higher mortality compared to neighboring Western countries. This is probably related to lifestyle, which can be theoretically modified not only by individual choice, but also aided by policies proposed towards reducing the consumption of alcohol and tobacco at state level, and by local politicians. Paradoxically, aggressive marketing campaigns of tobacco companies, coupled with historically a very high alcohol consumption, have made Eastern European countries an ideal place to implement effective and measurable public health campaigns.
Do you have any evidence this is the case here in Brno?
Yes, certainly, thanks to the Kardiovize Brno 2030 project. Since its start, in 2011, is the most comprehensive cardiovascular prevention program in Central and Eastern Europe. It has analyzed the health of the population of the city of Brno, as well as mapped cardiovascular risk factors in as much as one percent of its citizens, providing strength to our findings. Results showed a very high proportion of men (91%) and women (79%) reporting less than recommended fruit or vegetable intake, it also found that over a quarter of participants were smokers. This, together with other lifestyle factors may affect the rate of cardiovascular disease in Brno.
We are helping disseminate this information through scientific publications and conferences. Kardiovize Brno 2030 is aiming to a wider audience, so that programs looking at improving risk factors work not only in Brno, but throughout the country.
And are we able to contribute to the implementation of specific programs?
This is, of course, the BIG question, are we able to translate research into practice? I am optimistic. Experience from foreign settings provide evidence that raising awareness of risk factors such as cholesterol, high blood pressure or smoking can be effective at town, municipality level and beyond. Is a matter of addressing this issue outside the academic arena. Specific impacts such as reducing health care costs perhaps may be an argument strong enough to plan and implement an appropriate public health strategy.